Five years of AFC South dominance is on the line tonight in Nashville when the unbeaten Titans host the 3-3 Colts. A Tennessee win helps us look like a soothsayer with this July prediction. At 3-4, the Colts would still have to brace for New England, travel to Pittsburgh, and then play an improving Houston squad, one that always seems to play the colts tough. It doesn’t end there – road trips to San Diego, Cleveland and Jacksonville still remain. The end is nigh!

The problem with all this doom and gloom? As a rare October underdog, this is the perfect spot for the Colts’ defense to show up against a one-dimensional (and mouthy) Tennessee team, and Manning to work his fourth quarter magic for a 20-17 win. We’ll be pulling for the Titans, but we’re sensing a Colts victory.