The Big Lead

Which team has the best odds to cut down the net as March Madness enters Sweet 16?

Which program has the betting odds on their side as the Sweet 16 begins later this week?

By Tyler Reed

Duke Blue Devils guard Tyrese Proctor and Duke Blue Devils center Khaman Maluach reacts after a play against the Baylor Bears during the second half in the second round of the NCAA Tournament at Lenovo Center.
Duke Blue Devils guard Tyrese Proctor and Duke Blue Devils center Khaman Maluach reacts after a play against the Baylor Bears during the second half in the second round of the NCAA Tournament at Lenovo Center. / Bob Donnan-Imagn Images
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The first weekend of the NCAA Tournament has come and gone, and now, college basketball fans are getting to the meat of the Big Dance.

The Sweet 16 is set, and some familiar names have made the second round, including the Kentucky Wildcats, who haven't made it to the second weekend of the NCAA Tournament since 2019.

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However, just who has the best chance to cut down the nets at the end of March Madness? According to BetUS, it could be the Duke Blue Devils that call themselves champions when it is all said and done.

The betting site has given the Blue Devils the best chance to win the national title with +225 odds. The rest of the teams in the Sweet 16 have the following odds to win it all.

+375 Florida
+500 Auburn
+500 Houston
+1600 Alabama
+1600 Tennessee
+2000 Texas Tech
+2200 Michigan State
+3500 Maryland
+4000 Arizona
+5000 Kentucky
+6500 Purdue
+6500 Michigan
+6500 BYU
+8000 Ole Miss
+10000 Arkansas

All four number-one seeds have the best betting odds to win the national championship; however, the Houston Cougars and Auburn Tigers are tied with +500 odds.

John Calipar
Razorbacks head coach John Calipari during the first half of a second round men’s NCAA Tournament game against the St. John's Red Storm at Amica Mutual Pavilion. / Gregory Fisher-Imagn Images

John Calipari and the Arkansas Razorbacks have the worst odds to become the champions. The Razorbacks are the lowest seed to advance to the Sweet 16.

March is a time when you can throw away the odds, as the madness normally intervenes. However, fans of the Blue Devils have to like their chances.

Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

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